Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50409567'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409567 (CHEMBL445582) Show SMILES Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(=C3N)c3ccsc3)C2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O |c:21| Show InChI InChI=1S/C29H47N3O8S2Si2/c1-18-15-32(26(34)31(8)24(18)33)25-23(39-44(11,12)28(5,6)7)29(20(38-25)16-37-43(9,10)27(2,3)4)22(30)21(42(35,36)40-29)19-13-14-41-17-19/h13-15,17,20,23,25H,16,30H2,1-12H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in CEM cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409567 (CHEMBL445582) Show SMILES Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(=C3N)c3ccsc3)C2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O |c:21| Show InChI InChI=1S/C29H47N3O8S2Si2/c1-18-15-32(26(34)31(8)24(18)33)25-23(39-44(11,12)28(5,6)7)29(20(38-25)16-37-43(9,10)27(2,3)4)22(30)21(42(35,36)40-29)19-13-14-41-17-19/h13-15,17,20,23,25H,16,30H2,1-12H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in MT-4 cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair