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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50470144'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50470144
PNG
(CHEMBL43263)
Show SMILES CN(C)CCCOc1ccc(NC(=O)Cc2ccc(Cl)cc2C(=O)c2ccccc2)cc1
Show InChI InChI=1S/C26H27ClN2O3/c1-29(2)15-6-16-32-23-13-11-22(12-14-23)28-25(30)17-20-9-10-21(27)18-24(20)26(31)19-7-4-3-5-8-19/h3-5,7-14,18H,6,15-17H2,1-2H3,(H,28,30)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 443n/an/an/an/an/an/a



Glaxo Research and Development Limited

Curated by ChEMBL


Assay Description
Inhibitory activity against HIV-1 reverse transcriptase

J Med Chem 38: 1657-65 (1995)


Article DOI: 10.1021/jm00010a010
BindingDB Entry DOI: 10.7270/Q27947DP
More data for this
Ligand-Target Pair