Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50533354'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533354 (CHEMBL4455962) Show SMILES On1c(=O)cc(Nc2ccc(cc2)-c2ccc(Cl)cc2)[nH]c1=O Show InChI InChI=1S/C16H12ClN3O3/c17-12-5-1-10(2-6-12)11-3-7-13(8-4-11)18-14-9-15(21)20(23)16(22)19-14/h1-9,18,23H,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in nonspecific internal cleavage using HTS...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533354 (CHEMBL4455962) Show SMILES On1c(=O)cc(Nc2ccc(cc2)-c2ccc(Cl)cc2)[nH]c1=O Show InChI InChI=1S/C16H12ClN3O3/c17-12-5-1-10(2-6-12)11-3-7-13(8-4-11)18-14-9-15(21)20(23)16(22)19-14/h1-9,18,23H,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in RNA 5'-end directed cleavage using HTS3...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50533354 (CHEMBL4455962) Show SMILES On1c(=O)cc(Nc2ccc(cc2)-c2ccc(Cl)cc2)[nH]c1=O Show InChI InChI=1S/C16H12ClN3O3/c17-12-5-1-10(2-6-12)11-3-7-13(8-4-11)18-14-9-15(21)20(23)16(22)19-14/h1-9,18,23H,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of RNase H activity of full length recombinant HIV1 reverse transcriptase assessed as reduction in DNA 3'-end cleavage using HTS2 substrat...				J Med Chem 59: 2648-59 (2016) Article DOI: 10.1021/acs.jmedchem.5b01879 BindingDB Entry DOI: 10.7270/Q2QN6B8P
					More data for this Ligand-Target Pair