Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50540698'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540698 (CHEMBL4644576) Show SMILES CCOC(=O)c1cc(n[nH]1)-c1cn(Cc2ccc(F)cc2)cc1-c1ccc(OCC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C31H27FN4O4/c1-2-39-31(38)29-16-28(34-35-29)27-19-36(17-21-8-12-23(32)13-9-21)18-26(27)22-10-14-25(15-11-22)40-20-30(37)33-24-6-4-3-5-7-24/h3-16,18-19H,2,17,20H2,1H3,(H,33,37)(H,34,35)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
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