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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50027805'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50027805
PNG
(CHEMBL3338534)
Show SMILES Cc1cc(C)c(Oc2cc(Nc3ccc(cc3)C#N)ncc2C(=O)NCC#C)c(C)c1
Show InChI InChI=1S/C25H22N4O2/c1-5-10-27-25(30)21-15-28-23(29-20-8-6-19(14-26)7-9-20)13-22(21)31-24-17(3)11-16(2)12-18(24)4/h1,6-9,11-13,15H,10H2,2-4H3,(H,27,30)(H,28,29)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 70n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase assessed as reduction in biotin-dUTP incorporation using poly(rA)-oligo(dT) as template/primer and digoxigen...

Eur J Med Chem 87: 52-62 (2014)


Article DOI: 10.1016/j.ejmech.2014.09.054
BindingDB Entry DOI: 10.7270/Q2NP260N
More data for this
Ligand-Target Pair