Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50105464 (2,7-Dimethyl-acridine-3,6-diamine | CHEMBL329221) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri Curated by ChEMBL | Assay Description Inhibition of HIV-1 reverse transcriptase using Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assay | Bioorg Med Chem Lett 22: 4844-8 (2012) Article DOI: 10.1016/j.bmcl.2012.05.041 BindingDB Entry DOI: 10.7270/Q2SJ1PG6 | |||||||||||
More data for this Ligand-Target Pair |