Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50467329'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50467329 (CHEMBL74239) Show SMILES Nc1cc(Cc2c(Cl)cccc2Cl)nc(Nc2ccc(cc2)C#N)n1 Show InChI InChI=1S/C18H13Cl2N5/c19-15-2-1-3-16(20)14(15)8-13-9-17(22)25-18(24-13)23-12-6-4-11(10-21)5-7-12/h1-7,9H,8H2,(H3,22,23,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of HIV1 LAI reverse transcriptase infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by MTT assay				Eur J Med Chem 158: 371-392 (2018) Article DOI: 10.1016/j.ejmech.2018.09.013 BindingDB Entry DOI: 10.7270/Q2V98BRH
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50467329 (CHEMBL74239) Show SMILES Nc1cc(Cc2c(Cl)cccc2Cl)nc(Nc2ccc(cc2)C#N)n1 Show InChI InChI=1S/C18H13Cl2N5/c19-15-2-1-3-16(20)14(15)8-13-9-17(22)25-18(24-13)23-12-6-4-11(10-21)5-7-12/h1-7,9H,8H2,(H3,22,23,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...				Eur J Med Chem 158: 371-392 (2018) Article DOI: 10.1016/j.ejmech.2018.09.013 BindingDB Entry DOI: 10.7270/Q2V98BRH
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50467329 (CHEMBL74239) Show SMILES Nc1cc(Cc2c(Cl)cccc2Cl)nc(Nc2ccc(cc2)C#N)n1 Show InChI InChI=1S/C18H13Cl2N5/c19-15-2-1-3-16(20)14(15)8-13-9-17(22)25-18(24-13)23-12-6-4-11(10-21)5-7-12/h1-7,9H,8H2,(H3,22,23,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y188L mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...				Eur J Med Chem 158: 371-392 (2018) Article DOI: 10.1016/j.ejmech.2018.09.013 BindingDB Entry DOI: 10.7270/Q2V98BRH
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50467329 (CHEMBL74239) Show SMILES Nc1cc(Cc2c(Cl)cccc2Cl)nc(Nc2ccc(cc2)C#N)n1 Show InChI InChI=1S/C18H13Cl2N5/c19-15-2-1-3-16(20)14(15)8-13-9-17(22)25-18(24-13)23-12-6-4-11(10-21)5-7-12/h1-7,9H,8H2,(H3,22,23,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...				Eur J Med Chem 158: 371-392 (2018) Article DOI: 10.1016/j.ejmech.2018.09.013 BindingDB Entry DOI: 10.7270/Q2V98BRH
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50467329 (CHEMBL74239) Show SMILES Nc1cc(Cc2c(Cl)cccc2Cl)nc(Nc2ccc(cc2)C#N)n1 Show InChI InChI=1S/C18H13Cl2N5/c19-15-2-1-3-16(20)14(15)8-13-9-17(22)25-18(24-13)23-12-6-4-11(10-21)5-7-12/h1-7,9H,8H2,(H3,22,23,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	299	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase L100I mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...				Eur J Med Chem 158: 371-392 (2018) Article DOI: 10.1016/j.ejmech.2018.09.013 BindingDB Entry DOI: 10.7270/Q2V98BRH
					More data for this Ligand-Target Pair