Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50484007'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50484007 (CHEMBL1802248) Show SMILES [H][C@@]1(CCc2c(C1)c(C)cc(O)c(=O)c2O)C(C)(O)CSCc1ccccc1 |r| Show InChI InChI=1S/C22H26O4S/c1-14-10-19(23)21(25)20(24)17-9-8-16(11-18(14)17)22(2,26)13-27-12-15-6-4-3-5-7-15/h3-7,10,16,26H,8-9,11-13H2,1-2H3,(H2,23,24,25)/t16-,22?/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute-Frederick Curated by ChEMBL					Assay Description Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...				J Med Chem 54: 4462-73 (2011) Article DOI: 10.1021/jm2000757 BindingDB Entry DOI: 10.7270/Q26T0QH5
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