Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50484011'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50484011 (CHEMBL1802245) Show SMILES [H][C@@]1(CCc2c(C1)c(C)cc(O)c(=O)c2O)C(C)(O)CNc1ccccc1 |r| Show InChI InChI=1S/C21H25NO4/c1-13-10-18(23)20(25)19(24)16-9-8-14(11-17(13)16)21(2,26)12-22-15-6-4-3-5-7-15/h3-7,10,14,22,26H,8-9,11-12H2,1-2H3,(H2,23,24,25)/t14-,21?/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute-Frederick Curated by ChEMBL					Assay Description Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...				J Med Chem 54: 4462-73 (2011) Article DOI: 10.1021/jm2000757 BindingDB Entry DOI: 10.7270/Q26T0QH5
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