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Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50501060'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50501060
PNG
(CHEMBL3798153)
Show SMILES Clc1cc(Cl)cc(COCn2c(COCc3ccccc3)cc(=O)[nH]c2=O)c1
Show InChI InChI=1S/C20H18Cl2N2O4/c21-16-6-15(7-17(22)8-16)11-28-13-24-18(9-19(25)23-20(24)26)12-27-10-14-4-2-1-3-5-14/h1-9H,10-13H2,(H,23,25,26)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 410n/an/an/an/an/an/a



Volgograd State Medical University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 wild type reverse transcriptase p66/p51 using poly(rA) template and measured after 40 mins by picogreen based spectrofluorometry

Bioorg Med Chem 24: 2476-85 (2016)


Article DOI: 10.1016/j.bmc.2016.04.010
BindingDB Entry DOI: 10.7270/Q2B27Z9P
More data for this
Ligand-Target Pair