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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Reverse transcriptase protein' and Ligand = 'BDBM175339'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Reverse transcriptase protein


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM175339
PNG
(1-(4-chlorophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl...)
Show SMILES Clc1ccc(NC(=O)OC(CN2CCCc3ccccc23)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C24H22Cl2N2O2/c25-19-9-7-18(8-10-19)23(30-24(29)27-21-13-11-20(26)12-14-21)16-28-15-3-5-17-4-1-2-6-22(17)28/h1-2,4,6-14,23H,3,5,15-16H2,(H,27,29)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.38E+4n/an/an/an/an/an/a



Birla Institute of Technology & Science



Assay Description
The reaction mixture was set with template primer complex, RT enzyme and dNTPs in a lysis buffer with or without inhibitors. The reaction mixture was...


Bioorg Chem 64: 66-73 (2016)


Article DOI: 10.1016/j.bioorg.2015.12.005
BindingDB Entry DOI: 10.7270/Q2RB73CQ
More data for this
Ligand-Target Pair