Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Reverse transcriptase protein' and Ligand = 'BDBM50485779'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50485779 (CHEMBL2163850) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCc1ccc(cc1)C#N Show InChI InChI=1S/C25H20ClN3O3S/c1-15-9-16(2)11-20(10-15)33(31,32)24-21-12-19(26)7-8-22(21)29-23(24)25(30)28-14-18-5-3-17(13-27)4-6-18/h3-12,29H,14H2,1-2H3,(H,28,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase L100I mutant RNA-dependent DNA polymerase activity using poly(rA)/oligo(dT)10:1 and [3H]-dTTP substrate				J Med Chem 55: 6634-8 (2012) Article DOI: 10.1021/jm300477h BindingDB Entry DOI: 10.7270/Q24T6N7D
					More data for this Ligand-Target Pair
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50485779 (CHEMBL2163850) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCc1ccc(cc1)C#N Show InChI InChI=1S/C25H20ClN3O3S/c1-15-9-16(2)11-20(10-15)33(31,32)24-21-12-19(26)7-8-22(21)29-23(24)25(30)28-14-18-5-3-17(13-27)4-6-18/h3-12,29H,14H2,1-2H3,(H,28,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant RNA-dependent DNA polymerase activity using poly(rA)/oligo(dT)10:1 and [3H]-dTTP substrate				J Med Chem 55: 6634-8 (2012) Article DOI: 10.1021/jm300477h BindingDB Entry DOI: 10.7270/Q24T6N7D
					More data for this Ligand-Target Pair