Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM50309118'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50309118 (1-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-2-y...) Show SMILES NC1CCN(CC1)c1nc(cnc1N1CCCC1)-c1ccncc1 Show InChI InChI=1S/C18H24N6/c19-15-5-11-24(12-6-15)18-17(23-9-1-2-10-23)21-13-16(22-18)14-3-7-20-8-4-14/h3-4,7-8,13,15H,1-2,5-6,9-12,19H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human recombinant ROCK1				Bioorg Med Chem Lett 20: 1137-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.012 BindingDB Entry DOI: 10.7270/Q2QR4X7J
					More data for this Ligand-Target Pair