Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1 [1-535]' and Ligand = 'BDBM598572'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human))	BDBM598572 (N-(5-fluoro-2-(6-methyl-1,4-diazepan-1-yl)pyrimidi...) Show SMILES CC1CNCCN(C1)c1ncc(F)c(Nc2ccc3[nH]ncc3c2)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MP576K
					More data for this Ligand-Target Pair