Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1 [17-535]' and Ligand = 'BDBM362926'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human))	BDBM362926 (US9849138, 2) Show SMILES CN1c2ccc(Cl)cc2C(=O)N[C@@](C)(Cc2ccc(cc2)-c2ccncc2)C1=O |r| Show InChI InChI=1S/C23H20ClN3O2/c1-23(14-15-3-5-16(6-4-15)17-9-11-25-12-10-17)22(29)27(2)20-8-7-18(24)13-19(20)21(28)26-23/h3-13H,14H2,1-2H3,(H,26,28)/t23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of Michigan US Patent					Assay Description In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...				US Patent US9849138 (2017) BindingDB Entry DOI: 10.7270/Q2WH2S95
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