Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1 [17-535]' and Ligand = 'BDBM362931'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 [17-535] (Homo Sapiens (Human))	BDBM362931 (US9849138, 5) Show SMILES CN1c2c(Cl)cccc2C(=O)NC(Cc2ccc(cc2)-c2ccncc2)C1=O Show InChI InChI=1S/C22H18ClN3O2/c1-26-20-17(3-2-4-18(20)23)21(27)25-19(22(26)28)13-14-5-7-15(8-6-14)16-9-11-24-12-10-16/h2-12,19H,13H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of Michigan US Patent					Assay Description In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...				US Patent US9849138 (2017) BindingDB Entry DOI: 10.7270/Q2WH2S95
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