Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM169493'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169493 (US9079880, 26) Show SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3ccc(cc3)-c3ccncc3)sc2C1 |r| Show InChI InChI=1S/C30H29N5O2S/c1-34-17-13-25-27(19-34)38-30(32-25)33-28(36)24-5-2-4-23(18-24)26-6-3-16-35(26)29(37)22-9-7-20(8-10-22)21-11-14-31-15-12-21/h2,4-5,7-12,14-15,18,26H,3,6,13,16-17,19H2,1H3,(H,32,33,36)/t26-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169493 (US9079880, 26) Show SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3ccc(cc3)-c3ccncc3)sc2C1 |r| Show InChI InChI=1S/C30H29N5O2S/c1-34-17-13-25-27(19-34)38-30(32-25)33-28(36)24-5-2-4-23(18-24)26-6-3-16-35(26)29(37)22-9-7-20(8-10-22)21-11-14-31-15-12-21/h2,4-5,7-12,14-15,18,26H,3,6,13,16-17,19H2,1H3,(H,32,33,36)/t26-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair