Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM380213'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM380213 (1-benzyl-5-methyl-N-[4- (4-oxo-3,4- dihydrophthala...) Show SMILES Cc1cc(nn1Cc1ccccc1)C(=O)Nc1ccc(cc1)-c1n[nH]c(=O)c2ccccc12 Show InChI InChI=1S/C26H21N5O2/c1-17-15-23(30-31(17)16-18-7-3-2-4-8-18)26(33)27-20-13-11-19(12-14-20)24-21-9-5-6-10-22(21)25(32)29-28-24/h2-15H,16H2,1H3,(H,27,33)(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago					Assay Description The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...				J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q2445PSQ
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