Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50256227'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256227 (CHEMBL482310 | N3-(4-(1H-pyrazol-4-yl)phenyl)-N6,N...) Show SMILES CN(C)C(=O)c1ccc2OCC(Cc2c1)C(=O)Nc1ccc(cc1)-c1cn[nH]c1 Show InChI InChI=1S/C22H22N4O3/c1-26(2)22(28)15-5-8-20-16(9-15)10-17(13-29-20)21(27)25-19-6-3-14(4-7-19)18-11-23-24-12-18/h3-9,11-12,17H,10,13H2,1-2H3,(H,23,24)(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin)				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50256227 (CHEMBL482310 | N3-(4-(1H-pyrazol-4-yl)phenyl)-N6,N...) Show SMILES CN(C)C(=O)c1ccc2OCC(Cc2c1)C(=O)Nc1ccc(cc1)-c1cn[nH]c1 Show InChI InChI=1S/C22H22N4O3/c1-26(2)22(28)15-5-8-20-16(9-15)10-17(13-29-20)21(27)25-19-6-3-14(4-7-19)18-11-23-24-12-18/h3-9,11-12,17H,10,13H2,1-2H3,(H,23,24)(H,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay				Bioorg Med Chem Lett 18: 6406-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.080 BindingDB Entry DOI: 10.7270/Q2KK9BMC
					More data for this Ligand-Target Pair