Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50309124'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50309124 (1-(3-(pyrrolidin-1-yl)-6-(1H-pyrrolo[2,3-b]pyridin...) Show SMILES NC1CCN(CC1)c1nc(cnc1N1CCCC1)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C20H25N7/c21-14-5-11-27(12-6-14)20-19(26-9-1-2-10-26)24-13-17(25-20)15-3-7-22-18-16(15)4-8-23-18/h3-4,7-8,13-14H,1-2,5-6,9-12,21H2,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human recombinant ROCK2				Bioorg Med Chem Lett 20: 1137-40 (2010) Article DOI: 10.1016/j.bmcl.2009.12.012 BindingDB Entry DOI: 10.7270/Q2QR4X7J
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