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Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50311405'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))
BDBM50311405
PNG
(CHEMBL1077369 | N-((6R,9R,19R)-1-amino-19-(4-amino...)
Show SMILES [#7]-[#6]-[#6]-[#6]-[#6]-[#6@@H](-[#7]-[#6](=O)-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-c1ccc(s1)-c1ccnc(-[#7])n1)-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#7])=O |r|
Show InChI InChI=1S/C39H66N16O6S/c40-19-6-5-11-27(52-31(56)14-4-2-8-21-48-36(61)30-17-16-29(62-30)25-18-24-51-39(46)55-25)34(59)47-20-7-1-3-15-32(57)53-28(13-10-23-50-38(44)45)35(60)54-26(33(41)58)12-9-22-49-37(42)43/h16-18,24,26-28H,1-15,19-23,40H2,(H2,41,58)(H,47,59)(H,48,61)(H,52,56)(H,53,57)(H,54,60)(H4,42,43,49)(H4,44,45,50)(H2,46,51,55)/t26-,27-,28-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a<3n/an/an/an/an/a



University of Tartu

Curated by ChEMBL


Assay Description
Displacement of ARC583 from ROCK2


Bioorg Med Chem Lett 19: 6098-101 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.026
BindingDB Entry DOI: 10.7270/Q2JM29R4
More data for this
Ligand-Target Pair