Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50319721'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50319721 (CHEMBL1085082 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...) Show SMILES Clc1cc2c(cc[nH]c2=O)cc1NC(=O)C1CCNCC1 Show InChI InChI=1S/C15H16ClN3O2/c16-12-8-11-10(3-6-18-15(11)21)7-13(12)19-14(20)9-1-4-17-5-2-9/h3,6-9,17H,1-2,4-5H2,(H,18,21)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer-Ingelheim Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of ROCK2 by luciferase based ATP detection assay				Bioorg Med Chem Lett 20: 3746-9 (2010) Article DOI: 10.1016/j.bmcl.2010.04.069 BindingDB Entry DOI: 10.7270/Q2XD12MD
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50319721 (CHEMBL1085082 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...) Show SMILES Clc1cc2c(cc[nH]c2=O)cc1NC(=O)C1CCNCC1 Show InChI InChI=1S/C15H16ClN3O2/c16-12-8-11-10(3-6-18-15(11)21)7-13(12)19-14(20)9-1-4-17-5-2-9/h3,6-9,17H,1-2,4-5H2,(H,18,21)(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 20: 5153-6 (2010) Article DOI: 10.1016/j.bmcl.2010.07.014 BindingDB Entry DOI: 10.7270/Q2RR1ZDC
					More data for this Ligand-Target Pair