Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50338708'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50338708 (2-((2-(6-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)q...) Show SMILES COc1ccc2OCC(Cc2c1)c1nc(N(C)CCO)c2cc(ccc2n1)-c1cn[nH]c1 Show InChI InChI=1S/C24H25N5O3/c1-29(7-8-30)24-20-11-15(18-12-25-26-13-18)3-5-21(20)27-23(28-24)17-9-16-10-19(31-2)4-6-22(16)32-14-17/h3-6,10-13,17,30H,7-9,14H2,1-2H3,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2 by HTRF assay				Bioorg Med Chem Lett 21: 1844-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.039 BindingDB Entry DOI: 10.7270/Q20G3KFF
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