Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50358705'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50358705 (CHEMBL1922041) Show SMILES COc1cccc(CN(CCN2CCCC2)C(=O)c2cc3ccc(nc3n2C)-c2cn[nH]c2)c1 Show InChI InChI=1S/C26H30N6O2/c1-30-24(15-20-8-9-23(29-25(20)30)21-16-27-28-17-21)26(33)32(13-12-31-10-3-4-11-31)18-19-6-5-7-22(14-19)34-2/h5-9,14-17H,3-4,10-13,18H2,1-2H3,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 21: 7113-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.084 BindingDB Entry DOI: 10.7270/Q2F1905N
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