Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM50442808'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50442808 (CHEMBL2440732) Show SMILES COCCOC(=O)c1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1 Show InChI InChI=1S/C23H23N3O4/c1-29-11-12-30-23(28)18-4-2-3-16(13-18)21-14-17(5-6-19(21)15-24)22(27)26-20-7-9-25-10-8-20/h2-10,13-14H,11-12,15,24H2,1H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Amakem N.V. Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assay				Bioorg Med Chem Lett 23: 6442-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.040 BindingDB Entry DOI: 10.7270/Q2BC411W
					More data for this Ligand-Target Pair