Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-related GTP-binding protein RhoC' and Ligand = 'BDBM50481341'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-related GTP-binding protein RhoC (Homo sapiens)	BDBM50481341 (CHEMBL591079) Show SMILES Clc1ccc(NC(=O)CONC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C15H13ClN2O3/c16-12-6-8-13(9-7-12)17-14(19)10-21-18-15(20)11-4-2-1-3-5-11/h1-9H,10H2,(H,17,19)(H,18,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Medical School Curated by ChEMBL					Assay Description Inhibition of RhoA/C-mediated transcriptional response in human PC3 cells by serum response factor-luciferase reporter gene assay				Bioorg Med Chem Lett 20: 665-72 (2010) Article DOI: 10.1016/j.bmcl.2009.11.056 BindingDB Entry DOI: 10.7270/Q29S1TTD
					More data for this Ligand-Target Pair