Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rho-related GTP-binding protein RhoC' and Ligand = 'BDBM50481354'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-related GTP-binding protein RhoC (Homo sapiens)	BDBM50481354 (CHEMBL589373) Show SMILES FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)NCCc1cn(nn1)-c1ccccc1 Show InChI InChI=1S/C19H14F6N4O/c20-18(21,22)13-8-12(9-14(10-13)19(23,24)25)17(30)26-7-6-15-11-29(28-27-15)16-4-2-1-3-5-16/h1-5,8-11H,6-7H2,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Medical School Curated by ChEMBL					Assay Description Inhibition of RhoA/C-mediated transcriptional response in human PC3 cells by serum response factor-luciferase reporter gene assay				Bioorg Med Chem Lett 20: 665-72 (2010) Article DOI: 10.1016/j.bmcl.2009.11.056 BindingDB Entry DOI: 10.7270/Q29S1TTD
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