Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribose-phosphate pyrophosphokinase 1' and Ligand = 'BDBM493467'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribose-phosphate pyrophosphokinase 1 (Homo sapiens (Human))	BDBM493467 (US10981917, Example 168) Show SMILES Cc1c(Br)ccc2n(C\C=C\[C@H]3NCCC[C@@H]3O)cnc12 |r| Show InChI InChI=1S/C16H20BrN3O/c1-11-12(17)6-7-14-16(11)19-10-20(14)9-3-4-13-15(21)5-2-8-18-13/h3-4,6-7,10,13,15,18,21H,2,5,8-9H2,1H3/b4-3+/t13-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Daewoong Pharmaceutical Co., Ltd. US Patent					Assay Description In order to confirm the biological activities of the compounds prepared in Examples, % inhibition or IC50 values of PRS enzyme (phosphoribosylpyropho...				US Patent US10981917 (2021) BindingDB Entry DOI: 10.7270/Q2VH5RZ3
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