Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ribosomal protein S6 kinase beta-1 [T412E] (Homo sapiens (Human)) | BDBM224325 (US10080750, Compound 2 | US9321760, 2 | US9662330,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Merck Patent GmbH US Patent | Assay Description P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com... | US Patent US10080750 (2018) BindingDB Entry DOI: 10.7270/Q2WS8W9F | |||||||||||
More data for this Ligand-Target Pair |