Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1 [T412E]' and Ligand = 'BDBM365731'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase beta-1 [T412E] (Homo sapiens (Human))	BDBM365731 (5-Chloro-6-{(3S,4R)-4-[1-(2-dimethylamino-ethyl)-4...) Show SMILES CN(C)CCn1cc(nc1[C@H]1CCN(C[C@H]1F)c1ncnc(N)c1Cl)-c1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C23H25ClF5N7/c1-34(2)7-8-36-11-18(13-3-4-16(25)15(9-13)23(27,28)29)33-21(36)14-5-6-35(10-17(14)26)22-19(24)20(30)31-12-32-22/h3-4,9,11-12,14,17H,5-8,10H2,1-2H3,(H2,30,31,32)/t14-,17+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...				J Med Chem 50: 3651-60 (2007) BindingDB Entry DOI: 10.7270/Q2SJ1NXM
					More data for this Ligand-Target Pair