Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase beta-1 [T412E]' and Ligand = 'BDBM386034'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase beta-1 [T412E] (Homo sapiens (Human))	BDBM386034 (4-(4-(2-amino-1-(2-chlorophenyl)ethyl)piperazin-1-...) Show SMILES NCC(N1CCN(CC1)c1ncnc2NCC(=O)Nc12)c1ccccc1Cl Show InChI InChI=1S/C18H22ClN7O/c19-13-4-2-1-3-12(13)14(9-20)25-5-7-26(8-6-25)18-16-17(22-11-23-18)21-10-15(27)24-16/h1-4,11,14H,5-10,20H2,(H,24,27)(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin at Madison					Assay Description P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...				J Med Chem 51: 7243-52 (2008) BindingDB Entry DOI: 10.7270/Q26M394B
					More data for this Ligand-Target Pair