Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Runt-related transcription factor 1' and Ligand = 'BDBM29664'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Runt-related transcription factor 1 (Homo sapiens (Human))	BDBM29664 ((E)-2-Cyano-3-[2-(3,5-dimethyl-phenoxy)-9-methyl-4...) Show SMILES Cc1cc(C)cc(Oc2nc3c(C)cccn3c(=O)c2\C=C(/C#N)C(=O)NC2CCS(=O)(=O)C2)c1 Show InChI InChI=1S/C25H24N4O5S/c1-15-9-16(2)11-20(10-15)34-24-21(25(31)29-7-4-5-17(3)22(29)28-24)12-18(13-26)23(30)27-19-6-8-35(32,33)14-19/h4-5,7,9-12,19H,6,8,14H2,1-3H3,(H,27,30)/b18-12+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX
					More data for this Ligand-Target Pair
Runt-related transcription factor 1 (Homo sapiens (Human))	BDBM29664 ((E)-2-Cyano-3-[2-(3,5-dimethyl-phenoxy)-9-methyl-4...) Show SMILES Cc1cc(C)cc(Oc2nc3c(C)cccn3c(=O)c2\C=C(/C#N)C(=O)NC2CCS(=O)(=O)C2)c1 Show InChI InChI=1S/C25H24N4O5S/c1-15-9-16(2)11-20(10-15)34-24-21(25(31)29-7-4-5-17(3)22(29)28-24)12-18(13-26)23(30)27-19-6-8-35(32,33)14-19/h4-5,7,9-12,19H,6,8,14H2,1-3H3,(H,27,30)/b18-12+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P
					More data for this Ligand-Target Pair