Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Runt-related transcription factor 1' and Ligand = 'BDBM29671'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Runt-related transcription factor 1 (Homo sapiens (Human))	BDBM29671 ((E)-2-cyano-3-[4-keto-9-methyl-2-(4-piperonylpiper...) Show SMILES Cc1cccn2c1nc(N1CCN(Cc3ccc4OCOc4c3)CC1)c(\C=C(/C#N)C(N)=O)c2=O Show InChI InChI=1S/C25H24N6O4/c1-16-3-2-6-31-23(16)28-24(19(25(31)33)12-18(13-26)22(27)32)30-9-7-29(8-10-30)14-17-4-5-20-21(11-17)35-15-34-20/h2-6,11-12H,7-10,14-15H2,1H3,(H2,27,32)/b18-12+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX
					More data for this Ligand-Target Pair
Runt-related transcription factor 1 (Homo sapiens (Human))	BDBM29671 ((E)-2-cyano-3-[4-keto-9-methyl-2-(4-piperonylpiper...) Show SMILES Cc1cccn2c1nc(N1CCN(Cc3ccc4OCOc4c3)CC1)c(\C=C(/C#N)C(N)=O)c2=O Show InChI InChI=1S/C25H24N6O4/c1-16-3-2-6-31-23(16)28-24(19(25(31)33)12-18(13-26)22(27)32)30-9-7-29(8-10-30)14-17-4-5-20-21(11-17)35-15-34-20/h2-6,11-12H,7-10,14-15H2,1H3,(H2,27,32)/b18-12+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P
					More data for this Ligand-Target Pair