Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ryanodine receptor 1 [4317-4329]' and Ligand = 'BDBM430054'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ryanodine receptor 1 [4317-4329] ()	BDBM430054 (US10538528, Compound 41) Show SMILES CC(C)(C)NCCNc1ccc(nc1C1CCN(CC1)c1ncnc2NC(=O)C(C)(C)c12)-c1noc(n1)C(F)F Show InChI InChI=1S/C27H35F2N9O2/c1-26(2,3)33-11-10-30-16-6-7-17(21-35-24(20(28)29)40-37-21)34-19(16)15-8-12-38(13-9-15)23-18-22(31-14-32-23)36-25(39)27(18,4)5/h6-7,14-15,20,30,33H,8-13H2,1-5H3,(H,31,32,36,39)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pahrmaceutical Co., Ltd. US Patent					Assay Description Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...				US Patent US10538528 (2020) BindingDB Entry DOI: 10.7270/Q2MK6G95
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