BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'STE20-like serine/threonine-protein kinase' and Ligand = 'BDBM50577328'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
STE20-like serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50577328 (CHEMBL4875188) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity human SLK by binding displacement assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01579 BindingDB Entry DOI: 10.7270/Q2ST7TPK
TBA					More data for this Ligand-Target Pair
STE20-like serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50577328 (CHEMBL4875188) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SLK (unknown origin) assessed as transfer of radiolabelled phosphate group from ATP by reaction biology method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01579 BindingDB Entry DOI: 10.7270/Q2ST7TPK
TBA					More data for this Ligand-Target Pair
STE20-like serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50577328 (CHEMBL4875188) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of NanoLuc-fused SLK (unknown origin) expressed in HEK293T cells after 2 hrs by NanoBRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01579 BindingDB Entry DOI: 10.7270/Q2ST7TPK
TBA					More data for this Ligand-Target Pair