Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Rattus norvegicus) | BDBM50242014 (CHEMBL464006 | Morusin | Morusin, 3 | TCMDC-124149...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.87E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre of Experimental Medicine SAS Curated by ChEMBL | Assay Description Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | ACS Med Chem Lett 11: 1006-1013 (2020) Article DOI: 10.1021/acsmedchemlett.0c00047 BindingDB Entry DOI: 10.7270/Q2TB1BFV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Oryctolagus cuniculus) | BDBM50242014 (CHEMBL464006 | Morusin | Morusin, 3 | TCMDC-124149...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Centre of Experimental Medicine SAS Curated by ChEMBL | Assay Description Inhibition of SERCA1 in NewZealand rabbit skeletal muscle SR vesicles using ATP as substrate incubated for 2 mins followed by Ca2+ addition by NADH c... | ACS Med Chem Lett 11: 1006-1013 (2020) Article DOI: 10.1021/acsmedchemlett.0c00047 BindingDB Entry DOI: 10.7270/Q2TB1BFV | |||||||||||
More data for this Ligand-Target Pair |