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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Scavenger receptor class B member 1' and Ligand = 'BDBM50159548'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Scavenger receptor class B member 1


(Homo sapiens (Human))		BDBM50159548
PNG
(CHEMBL3785750)
Show SMILES COc1c(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc(cc1NS(=O)(=O)CCCNC(CO)(CO)CO)C(C)(C)C
Show InChI InChI=1S/C36H50N4O10S/c1-35(2,3)25-20-29(33(48-4)30(21-25)39-51(46,47)19-7-12-37-36(22-41,23-42)24-43)38-34(45)32(44)28-10-11-31(27-9-6-5-8-26(27)28)50-18-15-40-13-16-49-17-14-40/h5-6,8-11,20-21,37,39,41-43H,7,12-19,22-24H2,1-4H3,(H,38,45)
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 50n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me...

Bioorg Med Chem Lett 26: 1901-4 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.025
BindingDB Entry DOI: 10.7270/Q22R3TJ2
More data for this
Ligand-Target Pair