Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Secreted frizzled-related protein 1' and Ligand = 'BDBM50308711'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Secreted frizzled-related protein 1 (Homo sapiens (Human))	BDBM50308711 (4-{[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phe...) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N1CCC(CC1)NS(=O)(=O)c1cc(ccc1C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C25H23F3N2O8S3/c26-25(27,28)22-11-10-21(39(33,34)19-4-2-1-3-5-19)16-23(22)40(35,36)29-18-12-14-30(15-13-18)41(37,38)20-8-6-17(7-9-20)24(31)32/h1-11,16,18,29H,12-15H2,(H,31,32)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of fluorescence probe compound from human SFRP1 after 30 mins by fluorescence polarization assay				Bioorg Med Chem 18: 190-201 (2010) Article DOI: 10.1016/j.bmc.2009.11.002 BindingDB Entry DOI: 10.7270/Q2PZ58Z7
					More data for this Ligand-Target Pair
Secreted frizzled-related protein 1 (Homo sapiens (Human))	BDBM50308711 (4-{[4-({[5-(Phenylsulfonyl)-2-(trifluoromethyl)phe...) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N1CCC(CC1)NS(=O)(=O)c1cc(ccc1C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C25H23F3N2O8S3/c26-25(27,28)22-11-10-21(39(33,34)19-4-2-1-3-5-19)16-23(22)40(35,36)29-18-12-14-30(15-13-18)41(37,38)20-8-6-17(7-9-20)24(31)32/h1-11,16,18,29H,12-15H2,(H,31,32)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human recombinant SFRP1 expressed in human U2OS cells assessed as increase in Wnt signaling after 16 to 18 hrs by luciferase reporter g...				Bioorg Med Chem 18: 190-201 (2010) Article DOI: 10.1016/j.bmc.2009.11.002 BindingDB Entry DOI: 10.7270/Q2PZ58Z7
					More data for this Ligand-Target Pair