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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sepiapterin reductase' and Ligand = 'BDBM50515141'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sepiapterin reductase


(Homo sapiens (Human))		BDBM50515141
PNG
(CHEMBL4518154)
Show SMILES Oc1cncnc1C(=O)N1CCC2(CCC2)C1
Show InChI InChI=1S/C12H15N3O2/c16-9-6-13-8-14-10(9)11(17)15-5-4-12(7-15)2-1-3-12/h6,8,16H,1-5,7H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.55E+3n/an/an/an/an/an/a



Gr�nenthal GmbH

Curated by ChEMBL


Assay Description
Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis

J Med Chem 62: 6391-6397 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00218
BindingDB Entry DOI: 10.7270/Q2JW8J6W
More data for this
Ligand-Target Pair