Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase/endoribonuclease IRE1 (Homo sapiens (Human)) | BDBM416662 (3-allyl 7-methyl 8-hydroxy-5-oxo-4,5-dihydro-1H-ch...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent | Assay Description All compounds were evaluated by FRET-suppression assay in side-by-side experiments using 21b as a control inhibitor (Table 2). Protection of the alde... | US Patent US10323013 (2019) BindingDB Entry DOI: 10.7270/Q24J0HH9 | |||||||||||
More data for this Ligand-Target Pair |