Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase 26' and Ligand = 'BDBM451713'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 26 (Homo sapiens (Human))	BDBM451713 (6-(2-amino-5-(2- fluorophenyl)pyridin-3-yl)- 3,4-d...) Show SMILES Nc1ncc(cc1-c1ccc2C(=O)NCCc2c1)-c1ccccc1F Show InChI InChI=1S/C20H16FN3O/c21-18-4-2-1-3-15(18)14-10-17(19(22)24-11-14)12-5-6-16-13(9-12)7-8-23-20(16)25/h1-6,9-11H,7-8H2,(H2,22,24)(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020) BindingDB Entry DOI: 10.7270/Q2J67KZW
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