Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase 26' and Ligand = 'BDBM451761'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 26 (Homo sapiens (Human))	BDBM451761 (4-(6-amino-5-(1- oxoisoindolin-5-yl)pyridin-3- yl)...) Show SMILES CN(C1CC1)S(=O)(=O)c1ccc(c(F)c1)-c1cnc(N)c(c1)-c1ccc2C(=O)NCc2c1 Show InChI InChI=1S/C23H21FN4O3S/c1-28(16-3-4-16)32(30,31)17-5-7-18(21(24)10-17)15-9-20(22(25)26-11-15)13-2-6-19-14(8-13)12-27-23(19)29/h2,5-11,16H,3-4,12H2,1H3,(H2,25,26)(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020) BindingDB Entry DOI: 10.7270/Q2J67KZW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 26 (Homo sapiens (Human))	BDBM451761 (4-(6-amino-5-(1- oxoisoindolin-5-yl)pyridin-3- yl)...) Show SMILES CN(C1CC1)S(=O)(=O)c1ccc(c(F)c1)-c1cnc(N)c(c1)-c1ccc2C(=O)NCc2c1 Show InChI InChI=1S/C23H21FN4O3S/c1-28(16-3-4-16)32(30,31)17-5-7-18(21(24)10-17)15-9-20(22(25)26-11-15)13-2-6-19-14(8-13)12-27-23(19)29/h2,5-11,16H,3-4,12H2,1H3,(H2,25,26)(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
DANA-FARBER CANCER INSTITUTE, INC.; FONDAZIONE CENTRO SAN RAFFAELE US Patent					Assay Description Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...				US Patent US10710978 (2020) BindingDB Entry DOI: 10.7270/Q2J67KZW
					More data for this Ligand-Target Pair