BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase ATR' and Ligand = 'BDBM50456374'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase ATR


(Homo sapiens (Human))		BDBM50456374
PNG
(CHEMBL4210861)
Show SMILES Nc1ncnc2n(nc(-c3cnc4[nH]ccc4c3)c12)C1Cc2ccccc2C1
Show InChI InChI=1S/C21H17N7/c22-19-17-18(15-7-14-5-6-23-20(14)24-10-15)27-28(21(17)26-11-25-19)16-8-12-3-1-2-4-13(12)9-16/h1-7,10-11,16H,8-9H2,(H,23,24)(H2,22,25,26)
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 654n/an/an/an/an/an/a



Integral BioSciences, Pvt. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FLAG-tagged full length ATR expressed in mammalian cell line co-expressing human recombinant cMyc-tagged full length ...

Bioorg Med Chem Lett 27: 750-754 (2017)


Article DOI: 10.1016/j.bmcl.2017.01.045
BindingDB Entry DOI: 10.7270/Q28918G5
More data for this
Ligand-Target Pair