Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM26050'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM26050 ([2-(4-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-ind...) Show SMILES CN(C)CCOc1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1ccc2C(CCc2c1)N=O Show InChI InChI=1S/C28H28N4O2/c1-32(2)15-16-34-23-7-3-19(4-8-23)27-18-25(28(30-27)20-11-13-29-14-12-20)22-5-9-24-21(17-22)6-10-26(24)31-33/h3-5,7-9,11-14,17-18,26,30H,6,10,15-16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.700	n/a	n/a	n/a	7.5	22
GSK					Assay Description The kinase enzyme, fluorescent ligand and a variable concentration of test compound are incubated together to reach thermodynamic equilibrium under c...				Bioorg Med Chem Lett 18: 4373-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.070 BindingDB Entry DOI: 10.7270/Q26D5R86
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