Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50482019'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50482019 (CHEMBL1092523) Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)[nH]c34)cc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C25H23N7O3/c1-15(2)19-14-21(32(31-19)17-6-4-3-5-7-17)28-24(33)27-16-8-10-18(11-9-16)35-20-12-13-26-23-22(20)29-25(34)30-23/h3-15H,1-2H3,(H2,27,28,33)(H2,26,29,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human BRAF V600E mutant expressed in baculovirus system				J Med Chem 53: 2741-56 (2010) Article DOI: 10.1021/jm900607f BindingDB Entry DOI: 10.7270/Q2WD43CH
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50482019 (CHEMBL1092523) Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)[nH]c34)cc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C25H23N7O3/c1-15(2)19-14-21(32(31-19)17-6-4-3-5-7-17)28-24(33)27-16-8-10-18(11-9-16)35-20-12-13-26-23-22(20)29-25(34)30-23/h3-15H,1-2H3,(H2,27,28,33)(H2,26,29,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of BRAF V600E mutant ERK phosphorylation in human WM266.4 cells				J Med Chem 53: 2741-56 (2010) Article DOI: 10.1021/jm900607f BindingDB Entry DOI: 10.7270/Q2WD43CH
					More data for this Ligand-Target Pair