Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50482519'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50482519 (CHEMBL1214616) Show SMILES Oc1nc2c(Oc3cccc(NC(=O)c4cccc(OC(F)(F)F)c4)c3)ccnc2[nH]c1=O Show InChI InChI=1S/C21H13F3N4O5/c22-21(23,24)33-14-6-1-3-11(9-14)18(29)26-12-4-2-5-13(10-12)32-15-7-8-25-17-16(15)27-19(30)20(31)28-17/h1-10H,(H,26,29)(H,27,30)(H,25,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of B-Raf V600E mutant				J Med Chem 53: 5639-55 (2010) Article DOI: 10.1021/jm100383b BindingDB Entry DOI: 10.7270/Q22V2JZS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50482519 (CHEMBL1214616) Show SMILES Oc1nc2c(Oc3cccc(NC(=O)c4cccc(OC(F)(F)F)c4)c3)ccnc2[nH]c1=O Show InChI InChI=1S/C21H13F3N4O5/c22-21(23,24)33-14-6-1-3-11(9-14)18(29)26-12-4-2-5-13(10-12)32-15-7-8-25-17-16(15)27-19(30)20(31)28-17/h1-10H,(H,26,29)(H,27,30)(H,25,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cells				J Med Chem 53: 5639-55 (2010) Article DOI: 10.1021/jm100383b BindingDB Entry DOI: 10.7270/Q22V2JZS
					More data for this Ligand-Target Pair