Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf' and Ligand = 'BDBM50547984'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50547984 (CHEMBL4753081) Show SMILES Cl.Cc1cc(C(=O)Nc2c(Cl)ccc(NS(=O)(=O)c3cc(F)ccc3F)c2F)c2ncnc(N[C@H]3CC[C@H](N)CC3)c2c1 |r,wU:37.38,wD:34.34,(59.73,-45.54,;69.53,-50.16,;69.53,-48.62,;70.85,-47.85,;70.85,-46.32,;72.18,-45.55,;72.18,-44.01,;73.52,-46.32,;74.85,-45.55,;74.85,-44,;73.52,-43.24,;76.18,-43.23,;77.52,-44,;77.52,-45.55,;78.86,-46.32,;80.18,-45.54,;79.4,-44.2,;80.95,-44.19,;81.52,-46.31,;81.51,-47.86,;82.85,-48.63,;82.85,-50.17,;84.19,-47.86,;84.19,-46.3,;82.85,-45.53,;82.84,-43.99,;76.18,-46.32,;76.18,-47.86,;69.51,-45.55,;69.52,-44.02,;68.19,-43.25,;66.86,-44.02,;66.87,-45.55,;65.54,-46.32,;64.2,-45.55,;64.2,-44.02,;62.87,-43.25,;61.54,-44.02,;60.2,-43.24,;61.53,-45.56,;62.87,-46.33,;68.19,-46.31,;68.18,-47.85,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of of human recombinant His6-tagged B-Raf V600E mutant expressed in baculovirus infected cells co-expresing CDC37 in presence of [gamma33P...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00344 BindingDB Entry DOI: 10.7270/Q24Q7ZMD
					More data for this Ligand-Target Pair