Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf [V600E]' and Ligand = 'BDBM103713'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM103713 (US8563553, 138) Show SMILES CNc1nccc(n1)-c1nc([nH]c1-c1cccc(NS(C)(=O)=O)c1F)C1CC1 Show InChI InChI=1S/C18H19FN6O2S/c1-20-18-21-9-8-13(22-18)16-15(23-17(24-16)10-6-7-10)11-4-3-5-12(14(11)19)25-28(2,26)27/h3-5,8-10,25H,6-7H2,1-2H3,(H,23,24)(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	578	n/a	n/a	n/a	n/a	7.5	n/a
Novartis AG; IRM LLC US Patent					Assay Description Raf/Mek amplified luminescence proximity homogeneous assay.				US Patent US8563553 (2013) BindingDB Entry DOI: 10.7270/Q2ZP44R7
					More data for this Ligand-Target Pair