Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase B-raf [V600E]' and Ligand = 'BDBM126974'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM126974 (US8785459, 49) Show SMILES COc1cc2ncnc(Nc3cccc(O)c3)c2cc1-c1ccc(O)cc1 Show InChI InChI=1S/C21H17N3O3/c1-27-20-11-19-18(10-17(20)13-5-7-15(25)8-6-13)21(23-12-22-19)24-14-3-2-4-16(26)9-14/h2-12,25-26H,1H3,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	71.6	n/a	n/a	n/a	n/a	n/a	n/a
Development Center for Biotechnology US Patent					Assay Description Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...				US Patent US8785459 (2014) BindingDB Entry DOI: 10.7270/Q2M907BP
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