Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase Chk1' and Ligand = 'BDBM50192417'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50192417 (9-hydroxy-4-(4-pyridinyl)pyrrolo[3,4-c]carbazole-1...) Show SMILES Oc1ccc2[nH]c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccncc1 Show InChI InChI=1S/C19H11N3O3/c23-10-1-2-13-12(7-10)15-14(21-13)8-11(9-3-5-20-6-4-9)16-17(15)19(25)22-18(16)24/h1-8,21,23H,(H,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition at human Chk1 in presence of 4 uM ATP				J Med Chem 49: 4896-911 (2006) Article DOI: 10.1021/jm0512591 BindingDB Entry DOI: 10.7270/Q23778BD
					More data for this Ligand-Target Pair